Nhap mon cong nghe sinh hoc

Một Số Lĩnh Vực Ứng Dụng

Một số ứng dụng vào các lĩnh vực kinh tế xã hội

Công nghệ sinh học trong lĩnh vực y tế

Công nghệ sinh học trong lĩnh vực môi trường

Công nghệ sinh học trong lĩnh vực chế biến thực phẩm
Công nghệ sinh học trong lĩnh vực y tế

Vaccine
Recombinat vaccine
Conventional vaccine
Inactive
Weak
Gene transfer
Virus protein (Antigen)

FMDV
Marek
Gumboro
Newcastle
Transfer gene coated glycoprotein of Newcastle virus into smallpox
Transfer gene hemagglutini of influenza into pox virus
DNA vacine
Injection of pure DNA/RNA preparation to muscle
Uses of vector (vaccinia, E. coli., adenovirus, retroviruses..) for delivery gene
Reimplantation of autologous cells (cell of individual to be vaccinated)
in to which the gene has been transferd
Particle gun delivery of plasmid DNA which contain the gene
in an expression cassete
Disease diagnosis
1. Probes
DNA/RNA- PCR
2. Monoclonal antibodies
Ag isolation
injection
Spleen cells isolation
Marrow cancer cell (Myeloma )
Cell fusion
Hybridized cells selected in HAT
(hypoxathin aminopterin, Thymidine )
Cell culture (separated)
Antibody in medium
Y
Y
Y
Checking hybridized cells in medium
with MAb (reaction with Ag)
MAb Isolated from medium
Steps for MAb production
Disease diagnosis
3. Detect genetic disease
4. Disease treatment
5. Product from nonrecombinant organisms
(Micro-organisms, Plant and animail cell culture)
6. Product from recombinant organisms
(Genetically engineered Micro-Organism
Animal cell culture, transgenic plants)
Công nghệ sinh học trong lĩnh vực môi trường
ENVIRONMENTAL BIOTECHNOLOGY
Biotechnology is a useful tool that is delivering improved products and processes for the environmental sustainability. Biotechnology promises a range of benefits to manage the industrial waste water economically and effectively around the world.


Environmental Biotechnology is the multidisciplinary integration of sciences and engineering in order to utilize the huge biochemical potential of microorganisms, plants and parts thereof for the restoration and preservation of the environment and for the sustainable use of resources.
Cleaning of environment through nature’s scavengers
The field includes the application of microorganisms for

improvement of environmental quality

- discovery of microorganisms with metabolic

Potentials that can be employed for industrial applications

-Use of molecular methods for assessing the natural distribution of microbes in the environment and the ecological function they perform
NECESSITY OF THE DIFFERENCE
Concern about the environmental impact of genetically
engineered microorganisms has greatly constrained
the possibility of deliberately releasing recombinant
microbes for environmental remediation

 Using such recombinant microorganisms may be
possible within contained bioreactors organisms
The use of living microbes to
transform undesirable and
harmful substances into
non-toxic compounds.
The husbandry and management of naturally-occurring microbes
to degrade target pollutants for the purpose of restoring
contaminated environment.
BIOREMEDIATION

Exploits the metabolic capacities of microorganisms to
remove pollutants from the environment

BIOSTIMULATION
Relies on the natural activities of indigenous
microorganisms combined with the use of environmental
modifications, such as addition of mineral nutrients, to
stimulate the rate at which microbes metabolize pollutants

BIOAUGMENTATION
Involves the addition of cultures of microorganisms with
specific pollutant degrading capabilities to a polluted site
Biotechnology can play a major role in
pollution prevention, waste reduction,
bioconversion and energy cost savings.
Examples:
Pulp and Paper Industry
Textile Industry
Beverage Industry
Starch Industry
Petrochemicals
BIOTECHNOLOGY IN PULP AND
PAPER INDUSTRY
Biopulping uses enzymes to selectivity
degrade lignin and to break down wood
cell walls.
Biobleaching uses enzymes to bleach the pulp.
Biological decolourization uses bacteria or fungi.
Công nghệ sinh học trong lĩnh vực
nhiên liệu sinh hoc (biofuel)
BIOTECHNOLOGY IN PETROCHEMICALS
Cleaning of storage tank using enzymes
oil-spill clean-up using potential microbes
Công nghệ sinh học trong lĩnh vực chế biến thực phẩm
BIOTECHNOLOGY IN FOOD INDUSTRY
Enzymatic processing- Use of pectinases
and amylases in food processing
Effluent treatment of waste water using
potential microbes
Use of enzymes in starch processing
Biological removal of ammonia from
waste water
Effective and rapid treatment of waste
water using selective microbes
Lên men sinh tổng hợp enzim fructosyltransferaza từ A. niger trên thiết bị 14 lít
Đường chức năng fructo-oligosacarit (FOS)sản xuất bằng phương pháp enzim
Nghiên cứu sản xuất đường sorbitol
Mứt hoa quả các loại
Sản phẩm maltooligosacarit
Tôm chua lên men từ vi khuẩn lactic thuần chủng